Von Willebrand Disease Treatment – Orthodox Medicine

von Willebrand disease Treatment (VWD) is based on the type of VWD and the severity of symptoms.

The aim of therapy is to correct the acquired clotting problem. This is mostly and usually accomplished by raising the levels of VWF (von Willebrand factor) and factor VIII (another protein in the bloodstream).

Most cases of VWD are mild, so you may need treatment only if you have planned or abnormal conditions such as minor surgery procedures, tooth extractions, or after an accident.

If your condition does require treatment, there are several options and medicaments available.

DDAVP® {Desmopressin acetate} Injection

This medicine is nothing but a modified synthetic copy of vasopressin (a natural hormone), which works by assisting the body to release stored VWF into the bloodstream side by side by increasing the levels of factor VIII.

Side effects may include:

-local injection (site reactions),

-facial flushing,

-headache

-changes in blood pressure.

It is mostly given to patients as an infusion (by means of injection into a vein), but it can also be given subcutaneously (injected under the skin).

Stimate® (Desmopressin acetate) Nasal Spray 1.5 mg/ml

Stimate® (Desmopressin acetate) in the form of Nasal Spray 1.5 mg/ml is another type of Desmopressin, made as a high concentrate nasal spray.

Plusses:

– It can be used easily without the need of help like injections.

Stimate usage is recommended for people with mild or moderate Type 1 VWD.

Common side effects:

-facial flushing

-headache

Note that Desmopressin nasal spray is fabricated in two forms:

-low concentrate

-high concentrate

Low concentrate nasal spray is used to treat:

– diabetes insipidus

-bed wetting diseases

High concentrate nasal spray is aimed for von Willebrand disease Treatment

Factor replacement therapies – Factor Concentrates

Factor replacement therapies are medicaments given to replace the missing VWF in patients with VWD.

There are two kinds of replacement therapy:

-factor concentrates containing VWF, (preferred for von Willebrand disease Treatment because they are treated to kill any possible viral infection)

-cryoprecipitate.

Both Factor Concentrates are derived from fresh plasma and are set to be given by infusion.

Humate-P®

Humate-P® the Antihemophilic Factor/von Willebrand Factor Complex (Human). Is the only VWF concentrate approved in the United States for von Willebrand disease Treatment (it is used for all types of von Willebrand disease),

Humate-P is effective for most if not all bleeding episodes in all types of von Willebrand disease.

Usage:

-Humate-P is taken by injection. (Home infusion).

Antifibrinolytics (Local clotting agents)

Typical local clotting agents, or antifibrinolytics, usually taken as an injection or via oral tract (by mouth) (tablet, capsule, mouthwash or elixir).

Role:

They help protect clots and hold them in place (anti burst action) thus they help evacuate the reasons of thrombosis i.e. they decrease the possibilities of brain insults, heart attacks…

Usage:

antifibrinolytics can be used to stop bleeding in many circumstances and specially those related to digestive system problems, bleedings from mouth, nose, or gastrointestinal tract.

They are highly used to help control heavy bleeding during the menstrual period.

Oral contraceptive pills (Birth control pills)

OCP, Birth control pills, or oral contraceptives, can increase the levels of VWF, by affecting the glandular system as a whole, side by side by affecting the tonus of the white muscles and their mighty role in powering the immune system and fighting hypertension, though they increase the risk of clotting, and is not favored in women with hypotension or thrombolytic diseases

Oral contraceptive pills should be used with the supervision of a doctor specially when it is taken for von Willebrand disease Treatment.

Oral contraceptives are very useful for women with HMB syndrome (heavy menstrual bleeding syndrome).

A Unique Herbal Treatment For Equine Respiratory Disease

Sport and performance horses are extremely susceptible to lung disease. Even seemingly healthy horses are frequently affected. Studies have shown that 90-100% of sport horses tested have evidence of damage to their airways that can lead to Equine Reactive Airway Disease (RAD, also called Chronic Obstructive Pulmonary Disease or COPD)–a serious and career-ending condition. The first (and often only) early sign is decreased performance.

Herbs can be a safe, effective way to both prevent and treat Equine RAD/COPD. In fact, many herbs would help with some of the symptoms of this disease. For instance, Yarrow is often used for upper respiratory complaints.

Properties of the ideal herb for preventing and treating RAD/COPD would include:

  • Antioxidant, to reduce inflammation-causing molecules in the body that contribute to asthma
  • Antifungal, to inhibit mold particles that commonly cause respiratory disease in horses
  • Immune-modulating, to decrease the over-reactive immune response to allergens
  • Anti-inflammatory, to protect the lungs from the harmful effects of chronic inflammation
  • Free from heavy metal contamination, to prevent toxic build-up
  • Contain no substance prohibited by equine sports regulatory bodies such as USEF or racing commissions

Funtumia elastica is a medium-sized African rubber tree; its bark has a long history of use for respiratory complaints. Funtumia has important antioxidant, antifungal, anti-inflammatory, and antibiotic properties. It has no known toxicity, and is not barred by any equine sport governing body.

Natural compounds found in Funtumia include:

Anthocyanins: plant pigments that give berries their color (such as blueberries, blackberries, and cherries). Anthocyanins have been called “the mother lode in a gold mine of antioxidants.” Anthocyanins have shown specific benefit in reducing immune-stimulated inflammation, and are thought to be valuable in preventing the development of asthma.

Flavonoids: Vitamin C is the most familiar member of this class of plant-derived antioxidant compounds. Flavonoids are useful in both preventing and treating COPD, asthma, and other chronic lung diseases.

Plant sterols: natural plant steroids are safer than synthetic steroid drugs like prednisone and dexamethasone. Phytosterols have immuno-modulating effects–normalizing an over-reactive antibody response–as well as anti-inflammatory and anti-cancer properties.

Natural anti-fungals: Funtumia specifically inhibits growth of many molds, including Aspergillus, which is commonly associated with equine respiratory disease.

Tannins: These compounds have shown promise in the treatment of allergic inflammation and asthma.

Funtumia has demonstrated excellent safety (low toxicity) in multiple laboratory experiments, and has tested negative for heavy metals including cadmium, zinc, lead, chromium, and nickel. It does not contain any substances that are prohibited by any equine sport authority.

Preventing equine respiratory disease is easier—and smarter—than trying to treat established disease. Excellent hygiene, clean feeds, fresh air, and preventive therbal therapy could make all the difference for your horse.

New Treatment For Asthma

Asthma is a common disease in which the airways in the lung become inflamed and then narrow when muscles within the airway walls contract. Conventional therapies use two type of drugs viz short- term relievers and long-term controllers. While the relievers as the name suggests, treat the symptoms and eliminate them, giving short term relief, during an attack controllers are aimed at suppressing the inflammation in the airways. But this therapy may not be effective in treating severe or persistent conditions.

Bronchial themoplasty is a potential new asthma treatment currently undergoing clinical testing. Developed by a medical device company called Asthmatx Inc, this procedure has the potential to provide relief to asthma patients who do not respond to conventional treatment. A clinical trial was conducted on sixteen adults with mild to moderate asthma that did not respond to current asthma treatments. The results of the study are encouraging as 75 percent of the participants reported that the new treatment allowed to function better in daily activities and reduced peak expiratory flow readings.

Bronchioplasty is a new procedure, designed to reduce the tendency of narrowing of asthmatic airways. In this new procedure, the airways are treated in half-hour treatment sessions and may require up to three sessions to fully treat both lungs. The treatment, like any other endoscopy, is delivered through a bronchoscope. The procedure uses radio frequency energy to the airway to alter the ability of the muscles in the airway walls to constrict. When the constriction is reduced, it results in a reduction in the frequency as well as severity of asthma attacks in patients. Radio frequency energy is sent through a catheter inserted through the bronchoscope that heats the smooth muscle walls to approximately 149 º F.

The Blockbuster Herbal Formulation for Asthma http://www.healasthma.com

This procedure is expected to have an impact on the treatment of asthma in future. It is hoped that this procedure could be useful in reducing the severity and frequency of asthma attacks and be an alternative to the conventional asthma treatments although it is not intended to cure asthma.

NEW TREATMENT FOR ASTHMA